9. National Institute of General Medical Sciences, Medicines By Design: The Biological Eevolution in Pharmacology, NIH Publication #93-474., September 1993, 48 pp.

This short pamphlet surveys the current status of pharmacology and predicts some changes in pharmacology and pharmacognosy on the basis of present trends. The first chapter, "A Visit to the Doctor," predicts what pharmacology will be like in a quarter cuetnry. "Drugs From Nature, Then and Now," discusses the history of our use of medicinal plants. Only a pitiful few of them (5000 out of 300,000) have been studied for their possible medical usefulness. We do not know what effective therapeutic drugs may be destroyed in our clearing of forests and fields. A chapter on "How Your Body Responds to Drugs" outlines what happens to a drug -- and to you -- once it is administered. "What's Happening in Pharmacology Today" includes a section on "Drug Delivery" which outlines the new approaches to administering drugs. Finally, "Shaping Tomorrow's Drugs" includes discussion of rational drug design, protein engineering, and gene therapy -- three techniques being utilized by forward-looking pharmacologists.


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